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Formate—dihydrofolate ligase : ウィキペディア英語版
Formate—dihydrofolate ligase

In enzymology, a formate—dihydrofolate ligase () is an enzyme that catalyzes the chemical reaction
:ATP + formate + dihydrofolate \rightleftharpoons ADP + phosphate + 10-formyldihydrofolate
The 3 substrates of this enzyme are ATP, formate, and dihydrofolate, whereas its 3 products are ADP, phosphate, and 10-formyldihydrofolate.
This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. The systematic name of this enzyme class is formate:dihydrofolate ligase (ADP-forming). Other names in common use include formyltransferase, dihydrofolate, dihydrofolate formyltransferase, and formyl dihydrofolate synthase.
==References==


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